​Please get in touch informally to find out more about the below positions (rory.johnson[at]ucd.ie).

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Postdocs​

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Fellowship opportunities from the Irish Research Council https://research.ie/funding/goipd/

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Postdoc Opportunities: ERC Advanced Grant "REVOLVER"

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The Laboratory for Genomics of Long Noncoding RNA and Disease (GOLD Lab) is recruiting three postdoctoral researchers for a new ERC-funded programme applying directed evolution to regulatory long noncoding RNAs for the first time. The goal is to develop a deeper understanding of their molecular mechanisms and to engineer RNAs as a new class of therapeutic.

 

We have both experimental (‘wet’) and computational / bioinformatic (‘dry’) openings.

 

You will lead your own research area within a diverse, well-resourced team, and develop expertise at the intersection of RNA, evolution, genome editing and translational medicine. The project is supported by a team of world leading international collaborators.

 

We are looking for ambitious, independent researchers with a PhD and strong track record in one or more of:

• Quantitative evolutionary analysis: fitness landscapes, epistasis and the structure of genotype-phenotype maps; inference of variant fitness effects from high-throughput selection data; adaptive dynamics and the population genetics of selection experiments.

• Deep mutational scanning and multiplexed assays of variant effect (MAVEs): design, analysis or modelling of large-scale variant-function data.

• Sequence-function modelling: predictive or interpretable models mapping sequence to measured function, including model-guided design of mutational libraries.

• Experimental evolution and directed evolution: selection design, mutagenesis strategies, and analysis of evolving populations.

• RNA biology, genome editing and bioengineering: functional dissection of regulatory RNAs, CRISPR-based perturbation, and engineering of RNA molecules.

 

Duration: Fully funded for up to 5 years with competitive salary.

Start: March 2027 or soon after.

Location: Conway Institute, University College Dublin, Ireland.

 

More about us: The GOLD Lab studies lncRNAs and exploits them for medicine. Our approach is interdisciplinary (computational / experimental) with a particular strength in genome-editing methods. We collaborate closely with leading international consortia (including FANTOM, GENCODE) and research groups. Our core values are passion for science, respect for each other, team work and rigorous thinking. See our website at https://gold-lab.org

 

To apply: Send a brief email outlining your relevant experience and motivation, telling us where you saw our advert, with attached CV, to rory.johnson@ucd.ie with subject line "REVOLVER PD". Applications will be accepted on a rolling basis until positions are filled (check our website for updates).

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PhD Students​

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Unfortunately we do not have internal funding for new PhD students - due to volume, we cannot respond to unsolicited PhD requests.

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Below are some possible funding sources for interested students:

• China Scholarship Council (link)

• Irish Research Council https://research.ie/funding/goipg/

• Breakthrough Cancer Research https://www.breakthroughcancerresearch.ie/funding-information/

• Boehringer Ingelheim Fonds https://www.boehringer-ingelheim.com/procurement/research-development/boehringer-ingelheim-fonds

 

MSc Students

 

We have great projects, both experimental and bioinformatic, for highly motivated MSc students! (Unfortunately for administrative reasons, you must be self-funding). Please contact Rory for more information.​​

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