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Please get in touch informally to find out more about the below positions (rory.johnson[at]ucd.ie).

 

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We are Hiring!

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1. Various positions

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Are you an ambitious MSc or PhD student looking for a challenge at the forefront of genomics, computational biology and RNA therapeutics?

The Laboratory for Genomics of Long Noncoding RNAs and Disease (GOLD Lab) is hiring! Based in the Conway Institute at University College Dublin (Ireland), we are an interdisciplinary team of passionate researchers dedicated to understanding the roles of long non-coding RNAs in healthy and diseased cells. We love to create new tools based on CRISPR-Cas genome editing and bioinformatics, and we participate in various international collaborations and consortia. We strive to foster a supportive, collaborative and successful lab community. For more information, see below.
 

We presently have opportunities at both PhD and Postdoc level, for experimental and computational projects. Candidates should have either a quantitative (computer science, bioinformatics, statistics) or experimental biology background (molecular biology, cancer biology). To apply, send your CV and a brief motivation message to
Rory Johnson (rory.johnson [at] ucd.ie) with subject line “GOLD.recruitment”.

Website: https://www.gold-lab.org/
Twitter: @GOLDLab_UCD

Selected publications:
• TransCistor reveals the landscape of cis-regulatory long noncoding RNAs. Chouvardas et al. bioRxiv 2022
• Tumour mutations in long noncoding RNAs that enhance cell fitness. Esposito, Lanzós et al. bioRxiv 2022
• Multi-hallmark long noncoding RNA maps reveal non-small cell lung cancer vulnerabilities. Esposito, Polidori et al. Cell Genomics 2 (9) 100171 (2022)
• Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Rheinbay and PCAWG Consortium. Nature. 2020 Feb;578(7793):102-111.
• Hacking the Cancer Genome: Profiling Therapeutically Actionable Long Non-coding RNAs Using CRISPR-Cas9 Screening. Esposito R, et al. Cancer Cell. 2019 Apr 15;35(4):545-557
• Ancient exapted transposable elements promote nuclear enrichment of human long noncoding RNAs. Carlevaro-Fita J, Polidori T, Das M et al. Genome Research 2019 Feb;29(2):208-222.
• High-throughput annotation of full-length long noncoding RNAs with capture long-read sequencing. Lagarde J, Uszczynska-Ratajczak B et al. Nature Genetics 2017 Dec;49(12):1731-1740

(Full publication list here: https://tinyurl.com/goldlabpubs)

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Download job advert here

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2. PhD Project in Bioinformatics and RNA

Are you looking for a PhD in a world-leading research group at the forefront of Genomics, RNA and Bioinformatics?

This PhD project aims to apply computational techniques to address fundamental questions around the non-protein-coding “Dark Matter” of the human genome. More specifically, it will apply machine learning and data analysis to map and predict the function of the most widespread yet enigmatic class of genes: the long noncoding RNAs (lncRNAs). The project is supported by, and will take place within, the leading international collaboration in mapping lncRNAs - GENCODE (www.gencodegenes.org). The student will interact regularly with GENCODE members from USA and Europe.

This is a unique opportunity for a talented and motivated young scientist to train at the forefront of genomics.

The project is fully funded, and will be hosted at the prestigious Centre for Genomic Regulation in Barcelona, Spain. The successful candidate will have a demonstrated passion for genomics and have either a numerical background (bioinformatics, maths, statistics, computer science), or be a biologist with strong bioinformatics experience.

More information can be found here:
www.gencodegenes.org
https://www.gold-lab.org/
Lagarde et al
Uszczynska-Ratajczak et al

The scholarship is available to start immediately. Interested candidates should send their CV and a brief cover letter explaining why they are interested in this opportunity, to Rory Johnson (rory.johnson@ucd.ie) as soon as possible and before 15th November with subject line “lncRNA.PhD”.

 

Download job advert here

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MSc Students

 

We have great projects, both experimental and bioinformatic, for MSc students! (Unfortunately for administrative reasons, you must be self-funding). Please contact Rory for more information.

 

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PhD Students

 

Below are some possible funding sources for interested students:

• Irish Research Council https://research.ie/funding/goipg/

• Breakthrough Cancer Research https://www.breakthroughcancerresearch.ie/funding-information/

• Centre for Research Training in Genomic Data Science https://genomicsdatascience.ie/

• Boehringer Ingelheim Fonds https://www.boehringer-ingelheim.com/procurement/research-development/boehringer-ingelheim-fonds

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Postdocs

Irish Research Council https://research.ie/funding/goipd/

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